20mg
Tadalafil
Keeps blood flow elevated for up to 36 hours. A PDE5 inhibitor that enhances the nitric oxide pathway.
PDE5 Inhibitor
Prescription · Two Actives
Dual-PDE5 For Maximum Rigidity One Tablet
Tadalafil for the 36-hour window, sildenafil for fast onset. Two PDE5 inhibitors stacked in one sublingual tablet for men who want both.
HIPAACompliant
- 01Qualify2 MINShort online intake.
- 02ReviewSAME DAYA US doctor evaluates.
- 03CompoundOVERNIGHTCustom-made to your Rx.
- 04Deliver24 HRUnmarked package arrives.
Mach 1 (Rx)
HIPAACompliant
Sublingual tablet · Double Apple
Two Actives
Choose your Count Pack
Each Active
What's inside, and why it's there.
70mg
Sildenafil
The original PDE5 inhibitor. Faster onset than tadalafil, same nitric oxide pathway. For when timing matters more than window.
PDE5 Inhibitor
The old path
Separate visits. Separate scripts.
Unclear totals.
Retail pharmacies rarely carry compounded formulas tuned to your intake. Men stack separate visits, separate scripts, separate premiums, and still miss the combined formula.
The WellMensRX path
One intake. One tablet.
Unmarked package.
Everything in one compounded formula, reviewed same-day by a US-licensed physician and shipped overnight in plain packaging.
Refills on your schedule
You set the cadence. Pause, skip, or cancel in one click from your dashboard. No contract, no cancellation fees.
Cancel anytime Pause or skip Full dashboard control
Prices shown reflect first-order introductory pricing. Refills bill at the standard member rate, shown in your dashboard before each shipment. All products are prescription-only and dispensed following an online provider review; eligibility is not guaranteed. Free 24-hour shipping on approved orders where advertised. Final price confirmed at checkout. Not medical advice; treatment availability is determined by your provider.
Safety information
What to know before your intake.
Your reviewing physician screens for contraindications and interactions. Disclose everything — current prescriptions, OTC medications, supplements, and medical history — during the intake so they can catch anything below that would make this formula unsafe for you.
PDE5 inhibitors (tadalafil, sildenafil, vardenafil)
- Do not take with nitrates (nitroglycerin, isosorbide) or recreational nitrites ("poppers") — combination can cause severe, potentially fatal low blood pressure.
- Use caution with alpha-blockers (doxazosin, tamsulosin) and other blood-pressure medications — can cause lightheadedness or fainting.
- Not appropriate if you have had a recent heart attack, stroke, or severe cardiovascular disease, or have uncontrolled hypertension or hypotension.
- Seek emergency care for an erection lasting more than 4 hours (priapism) or sudden vision or hearing loss.
- Common side effects: headache, flushing, mild nasal congestion, back pain, indigestion. Usually mild and transient.
Do not share your prescription. Compounded medications are prepared specifically for the patient named on the label and should never be given, sold, or shared with another person. Keep out of reach of children and pets.
In their words
What members have said.
Attribution limited to initials, age, and state — full names are never published.
Both PDE5s in one dose was the draw. It's a lot — I don't take it every weekend — but when I do it delivers on the name.
W.C.
I stack this with pycnogenol from another product I'm on. My care team cleared the combo and it's been smooth.
J.B. combined
First time I used it I took a normal dose, nothing dramatic. It's not about intensity — it's about the fact that it actually held up for once.
R.F.
Two PDE5s is the kind of thing I'd have had to ask for off-label from three different doctors. Finding it on one prescription saved me six months.
P.H.
You feel it in the legs a little — heavy and warm. Then it shows up where you want it.
L.E.
My wife said it felt different, in a good way. I didn't need to ask what she meant.
N.A.
Mild heartburn the first couple times — gone once I started taking it earlier in the evening.
D.M.
I tried running mach 1 daily for two weeks and that was too much for me. It's a weekend or event tool, not a daily.
C.T. dose lesson
First round was strong, second round was the same night. I didn't think that was on the table anymore.
M.V.
I'm a big guy and the standard doses never quite landed. This one actually hits the mark.
S.W.
Collected from verified members, edited for length only. Individual results vary.
Before you qualify
Frequently Asked Questions
Formula
Why two PDE5 inhibitors in one tablet?
Tadalafil and sildenafil both unlock the same mechanism, but they run different curves. Sildenafil peaks hard and fast; tadalafil runs lower and longer. Stacking them covers the whole curve — the fast kick of sildenafil plus the 36-hour stability of tadalafil, in one sublingual tablet.
Tadalafil · Sildenafil
Fit
I've tried Viagra or Cialis and it wasn't enough. Will this be different?
This is exactly what Mach 1 is for. If a single-ingredient PDE5 at standard dose has not produced the firmness you want, dual-PDE5 is the mechanism-level next step before moving to injection therapies. Most men who feel under-served by the brand-name pills report a clear difference on the stack.
Step-up from single PDE5
Onset
How fast does it hit and how long does it last?
Sildenafil drives the early window — typically inside 30 minutes sublingual. Tadalafil carries the back end out to roughly 36 hours. You get the sharp onset of one and the long window of the other from a single dose.
Fast onset · 36-hour tail
Cost
What does it cost per dose?
The 18-count pack comes in at $7.97 per dose. Getting the equivalent through retail would mean two separate prescriptions, two copays, and you'd still not be taking them in the same tablet. Mach 1 is the compounded, combined version.
From $7.97 per dose
Proof
What if a single-ingredient pill hasn't worked for me before?
That is the exact reason Mach 1 exists. Standard Viagra and Cialis miss roughly one in three men at standard dose — usually because one receptor curve alone does not cover the whole window. The dual-PDE5 stack closes that gap without moving to injections.
Built for under-responders
Escalation
What if Mach 1 still isn't enough?
Ignite is the next step — triple-active with apomorphine layered on top of both PDE5 inhibitors. It exists for the small group of men where mechanics alone still aren't closing the gap. Your prescriber can route you there from the same intake.
Next: Ignite
